1.

New York Islanders
 vs. Calgary Flames

September 29, 2010
Wednesday, 6:00 pm

 2.

New York Islanders
 vs. Montreal Canadiens

October 2, 2010
Saturday, 7:00 pm

 3.

New York Islanders
 vs. New Jersey Devils

October 2, 2010
Saturday, 7:00 pm

 4.

New York Islanders
 vs. Dallas Stars

October 9, 2010
Saturday, 7:00 pm

 5.

New York Islanders
 vs. New York Rangers

October 11, 2010
Monday, 1:00 pm

 6.

New York Islanders
 vs. Colorado Avalanche

October 16, 2010
Saturday, 7:00 pm

 7.

New York Islanders
 vs. Montreal Canadiens

October 29, 2010
Friday, 7:00 pm

 8.

New York Islanders
 vs. Philadelphia Flyers

November 6, 2010
Saturday, 7:00 pm

 9.

New York Islanders
 vs. Tampa Bay Lightning

November 17, 2010
Wednesday, 7:00 pm

 10.

New York Islanders
 vs. Florida Panthers

November 20, 2010
Saturday, 7:00 pm

 11.

New York Islanders
 vs. Columbus Blue Jackets

November 24, 2010
Wednesday, 7:00 pm

 12.

New York Islanders
 vs. New Jersey Devils

November 26, 2010
Friday, 1:00 pm

 13.

New York Islanders
 vs. New York Rangers

December 2, 2010
Thursday, 7:00 pm

 14.

New York Islanders
 vs. Philadelphia Flyers

December 5, 2010
Sunday, 1:00 pm

 15.

New York Islanders
 vs. Atlanta Thrashers

December 11, 2010
Saturday, 7:00 pm

 16.

New York Islanders
 vs. Anaheim Ducks

December 16, 2010
Thursday, 7:00 pm

 17.

New York Islanders
 vs. Phoenix Coyotes

December 18, 2010
Saturday, 7:00 pm

 18.

New York Islanders
 vs. Tampa Bay Lightning

December 22, 2010
Wednesday, 7:00 pm

 19.

New York Islanders
 vs. Montreal Canadiens

December 26, 2010
Sunday, 7:00 pm

 20.

New York Islanders
 vs. Pittsburgh Penguins

December 29, 2010
Wednesday, 7:00 pm

 21.

New York Islanders
 vs. Vancouver Canucks

January 11, 2011
Tuesday, 7:00 pm

 22.

New York Islanders
 vs. Ottawa Senators

January 13, 2011
Thursday, 7:00 pm

 23.

New York Islanders
 vs. Buffalo Sabres

January 15, 2011
Saturday, 7:00 pm

 24.

New York Islanders
 vs. New Jersey Devils

January 17, 2011
Monday, 1:00 pm

 25.

New York Islanders
 vs. Washington Capitals

January 20, 2011
Thursday, 7:00 pm

 26.

New York Islanders
 vs. Buffalo Sabres

January 23, 2011
Sunday, 3:00 pm

 27.

New York Islanders
 vs. Carolina Hurricanes

January 26, 2011
Wednesday, 7:00 pm

 28.

New York Islanders
 vs. Ottawa Senators

February 5, 2011
Saturday, 7:00 pm

 29.

New York Islanders
 vs. Toronto Maple Leafs

February 8, 2011
Tuesday, 7:00 pm

 30.

New York Islanders
 vs. Pittsburgh Penguins

February 11, 2011
Friday, 7:00 pm

 31.

New York Islanders
 vs. Boston Bruins

February 17, 2011
Thursday, 7:00 pm

 32.

New York Islanders
 vs. Los Angeles Kings

February 19, 2011
Saturday, 7:00 pm

 33.

New York Islanders
 vs. Florida Panthers

February 21, 2011
Monday, 1:00 pm

 34.

New York Islanders
 vs. Washington Capitals

February 26, 2011
Saturday, 7:00 pm

 35.

New York Islanders
 vs. Minnesota Wild

March 2, 2011
Wednesday, 7:00 pm

 36.

New York Islanders
 vs. St. Louis Blues

March 5, 2011
Saturday, 1:00 pm

 37.

New York Islanders
 vs. New Jersey Devils

March 6, 2011
Sunday, 1:00 pm

 38.

New York Islanders
 vs. Toronto Maple Leafs

March 8, 2011
Tuesday, 7:00 pm

 39.

New York Islanders
 vs. Boston Bruins

March 11, 2011
Friday, 7:00 pm

 40.

New York Islanders
 vs. Atlanta Thrashers

March 24, 2011
Thursday, 7:00 pm

 41.

New York Islanders
 vs. Philadelphia Flyers

March 26, 2011
Saturday, 7:00 pm

 42.

New York Islanders
 vs. New York Rangers

March 31, 2011
Thursday, 7:00 pm

 43.

New York Islanders
 vs. Carolina Hurricanes

April 2, 2011
Saturday, 7:00 pm

 44.

New York Islanders
 vs. Pittsburgh Penguins

April 8, 2011
Friday, 7:00 pm