1.

Toronto Maple Leafs
 vs. Ottawa Senators

September 22, 2010
Wednesday, 7:00 pm

 2.

Toronto Maple Leafs
 vs. Philadelphia Flyers

September 23, 2010
Thursday, 7:00 pm

 3.

Toronto Maple Leafs
 vs. Philadelphia Flyers

September 24, 2010
Friday, 7:00 pm

 4.

Toronto Maple Leafs
 vs. Buffalo Sabres

September 27, 2010
Monday, 7:00 pm

 5.

Toronto Maple Leafs
 vs. Detroit Red Wings

October 2, 2010
Saturday, 7:00 pm

 6.

Toronto Maple Leafs
 vs. Montreal Canadiens

October 7, 2010
Thursday, 7:00 pm

 7.

Toronto Maple Leafs
 vs. Ottawa Senators

October 9, 2010
Saturday, 7:00 pm

 8.

Toronto Maple Leafs
 vs. New York Islanders

October 18, 2010
Monday, 7:00 pm

 9.

Toronto Maple Leafs
 vs. New York Rangers

October 21, 2010
Thursday, 7:00 pm

 10.

Toronto Maple Leafs
 vs. Florida Panthers

October 26, 2010
Tuesday, 7:00 pm

 11.

Toronto Maple Leafs
 vs. New York Rangers

October 30, 2010
Saturday, 7:00 pm

 12.

Toronto Maple Leafs
 vs. Ottawa Senators

November 2, 2010
Tuesday, 7:00 pm

 13.

Toronto Maple Leafs
 vs. Buffalo Sabres

November 6, 2010
Saturday, 7:00 pm

 14.

Toronto Maple Leafs
 vs. Vancouver Canucks

November 13, 2010
Saturday, 7:00 pm

 15.

Toronto Maple Leafs
 vs. Nashville Predators

November 16, 2010
Tuesday, 7:00 pm

 16.

Toronto Maple Leafs
 vs. New Jersey Devils

November 18, 2010
Thursday, 7:00 pm

 17.

Toronto Maple Leafs
 vs. Dallas Stars

November 22, 2010
Monday, 7:00 pm

 18.

Toronto Maple Leafs
 vs. Tampa Bay Lightning

November 30, 2010
Tuesday, 7:00 pm

 19.

Toronto Maple Leafs
 vs. Edmonton Oilers

December 2, 2010
Thursday, 7:00 pm

 20.

Toronto Maple Leafs
 vs. Boston Bruins

December 4, 2010
Saturday, 7:00 pm

 21.

Toronto Maple Leafs
 vs. Philadelphia Flyers

December 9, 2010
Thursday, 7:00 pm

 22.

Toronto Maple Leafs
 vs. Montreal Canadiens

December 11, 2010
Saturday, 7:00 pm

 23.

Toronto Maple Leafs
 vs. Atlanta Thrashers

December 20, 2010
Monday, 7:00 pm

 24.

Toronto Maple Leafs
 vs. Carolina Hurricanes

December 28, 2010
Tuesday, 7:00 pm

 25.

Toronto Maple Leafs
 vs. Columbus Blue Jackets

December 30, 2010
Thursday, 7:00 pm

 26.

Toronto Maple Leafs
 vs. Boston Bruins

January 3, 2011
Monday, 7:00 pm

 27.

Toronto Maple Leafs
 vs. St. Louis Blues

January 6, 2011
Thursday, 7:00 pm

 28.

Toronto Maple Leafs
 vs. Calgary Flames

January 15, 2011
Saturday, 7:00 pm

 29.

Toronto Maple Leafs
 vs. Anaheim Ducks

January 20, 2011
Thursday, 7:00 pm

 30.

Toronto Maple Leafs
 vs. Washington Capitals

January 22, 2011
Saturday, 7:00 pm

 31.

Toronto Maple Leafs
 vs. Florida Panthers

February 1, 2011
Tuesday, 7:00 pm

 32.

Toronto Maple Leafs
 vs. Carolina Hurricanes

February 3, 2011
Thursday, 7:00 pm

 33.

Toronto Maple Leafs
 vs. Atlanta Thrashers

February 7, 2011
Monday, 7:00 pm

 34.

Toronto Maple Leafs
 vs. New Jersey Devils

February 10, 2011
Thursday, 7:00 pm

 35.

Toronto Maple Leafs
 vs. Ottawa Senators

February 19, 2011
Saturday, 7:00 pm

 36.

Toronto Maple Leafs
 vs. New York Islanders

February 22, 2011
Tuesday, 7:00 pm

 37.

Toronto Maple Leafs
 vs. Pittsburgh Penguins

February 26, 2011
Saturday, 7:00 pm

 38.

Toronto Maple Leafs
 vs. Pittsburgh Penguins

March 2, 2011
Wednesday, 7:00 pm

 39.

Toronto Maple Leafs
 vs. Chicago Blackhawks

March 5, 2011
Saturday, 7:00 pm

 40.

Toronto Maple Leafs
 vs. Philadelphia Flyers

March 10, 2011
Thursday, 7:00 pm

 41.

Toronto Maple Leafs
 vs. Buffalo Sabres

March 12, 2011
Saturday, 7:00 pm

 42.

Toronto Maple Leafs
 vs. Tampa Bay Lightning

March 14, 2011
Monday, 7:00 pm

 43.

Toronto Maple Leafs
 vs. Boston Bruins

March 19, 2011
Saturday, 7:00 pm

 44.

Toronto Maple Leafs
 vs. Buffalo Sabres

March 29, 2011
Tuesday, 7:00 pm

 45.

Toronto Maple Leafs
 vs. Washington Capitals

April 5, 2011
Tuesday, 7:00 pm

 46.

Toronto Maple Leafs
 vs. Montreal Canadiens

April 9, 2011
Saturday, 7:00 pm